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Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis
Hemorrhagic cystitis is an inflammatory and ulcerative bladder condition associated with systemic chemotherapeutics, like cyclophosphomide. Earlier, we reported reactive oxygen species resulting from cyclophosphamide metabolite, acrolein, causes global methylation followed by silencing of DNA damage...
Autores principales: | Haldar, Subhash, Dru, Christopher, Mishra, Rajeev, Tripathi, Manisha, Duong, Frank, Angara, Bryan, Fernandez, Ana, Arditi, Moshe, Bhowmick, Neil A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171776/ https://www.ncbi.nlm.nih.gov/pubmed/27995963 http://dx.doi.org/10.1038/srep39257 |
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