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Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa

Plant knottins are of therapeutic interest due to their high metabolic stability and inhibitory activity against proteinases involved in human diseases. The only knottin-type proteinase inhibitor against porcine pancreatic elastase was first identified from the squash family in 1989. Here, we report...

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Detalles Bibliográficos
Autores principales:	Loo, Shining, Kam, Antony, Xiao, Tianshu, Nguyen, Giang K. T., Liu, Chuan Fa, Tam, James P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171801/ https://www.ncbi.nlm.nih.gov/pubmed/27991569 http://dx.doi.org/10.1038/srep39401

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