Evolution of multiple cell clones over a 29-year period of a CLL patient

Chronic lymphocytic leukaemia (CLL) is a frequent B-cell malignancy, characterized by recurrent somatic chromosome alterations and a low level of point mutations. Here we present single-nucleotide polymorphism microarray analyses of a single CLL patient over 29 years of observation and treatment, an...

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Detalles Bibliográficos
Autores principales: Zhao, Zhikun, Goldin, Lynn, Liu, Shiping, Wu, Liang, Zhou, Weiyin, Lou, Hong, Yu, Qichao, Tsang, Shirley X., Jiang, Miaomiao, Li, Fuqiang, McMaster, MaryLou, Li, Yang, Lin, Xinxin, Wang, Zhifeng, Xu, Liqin, Marti, Gerald, Li, Guibo, Wu, Kui, Yeager, Meredith, Yang, Huanming, Xu, Xun, Chanock, Stephen J., Li, Bo, Hou, Yong, Caporaso, Neil, Dean, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171825/
https://www.ncbi.nlm.nih.gov/pubmed/27982015
http://dx.doi.org/10.1038/ncomms13765

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