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Engineering orthogonal dual transcription factors for multi-input synthetic promoters

Synthetic biology has seen an explosive growth in the capability of engineering artificial gene circuits from transcription factors (TFs), particularly in bacteria. However, most artificial networks still employ the same core set of TFs (for example LacI, TetR and cI). The TFs mostly function via re...

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Detalles Bibliográficos
Autores principales: Brödel, Andreas K., Jaramillo, Alfonso, Isalan, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171851/
https://www.ncbi.nlm.nih.gov/pubmed/27982027
http://dx.doi.org/10.1038/ncomms13858