Cargando…
Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB
The deployment of multidrug efflux pumps is a powerful defence mechanism for Gram-negative bacterial cells when exposed to antimicrobial agents. The major multidrug efflux transport system in Escherichia coli, AcrAB–TolC, is a tripartite system using the proton-motive force as an energy source. The...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171871/ https://www.ncbi.nlm.nih.gov/pubmed/27982032 http://dx.doi.org/10.1038/ncomms13819 |