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A polymorphism of HMGA1 protects against proliferative diabetic retinopathy by impairing HMGA1-induced VEGFA expression
Diabetic retinopathy (DR) is a major complication of diabetes mellitus, and is the leading cause of blindness in working-age people. Usually, DR progresses from the asymptomatic non-proliferative DR that does not significantly alter vision, to proliferative DR (PDR), which can result in aberrant ret...
Autores principales: | Chiefari, Eusebio, Ventura, Valeria, Capula, Carmelo, Randazzo, Giorgio, Scorcia, Vincenzo, Fedele, Monica, Arcidiacono, Biagio, Nevolo, Maria Teresa, Bilotta, Francesco Luciano, Vitiello, Michela, Palmieri, Camillo, Gulletta, Elio, Fusco, Alfredo, Foti, Daniela, Vero, Raffaella, Brunetti, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171873/ https://www.ncbi.nlm.nih.gov/pubmed/27991577 http://dx.doi.org/10.1038/srep39429 |
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