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Distinct roles of short and long thymic stromal lymphopoietin isoforms in house dust mite-induced asthmatic airway epithelial barrier disruption

Loss of airway epithelial integrity contributes significantly to asthma pathogenesis. Thymic stromal lymphopoietin (TSLP) may have dual immunoregulatory roles. In inflammatory disorders of the bowel, the long isoform of TSLP (lfTSLP) promotes inflammation while the short isoform (sfTSLP) inhibits in...

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Detalles Bibliográficos
Autores principales: Dong, Hangming, Hu, Yahui, Liu, Laiyu, Zou, Mengchen, Huang, Chaowen, Luo, Lishan, Yu, Changhui, Wan, Xuan, Zhao, Haijin, Chen, JiaLong, Xie, Zhefan, Le, Yanqing, Zou, Fei, Cai, Shaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171874/
https://www.ncbi.nlm.nih.gov/pubmed/27996052
http://dx.doi.org/10.1038/srep39559