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Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer
Germline mutations in the CDH1 gene that produces E-cadherin have been implicated in the development of early-onset diffuse gastric cancer, termed hereditary diffuse gastric cancer. The mean age of gastric cancer diagnosis in affected individuals is 37 years. By age 80, CDH1 mutation carriers who fu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American College of Gastroenterology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171935/ https://www.ncbi.nlm.nih.gov/pubmed/28008412 http://dx.doi.org/10.14309/crj.2016.152 |