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Estrogen-induced SDF-1α production promotes the progression of ER-negative breast cancer via the accumulation of MDSCs in the tumor microenvironment

Estrogen plays a role in the processes of tumorigenesis, metastasis, and drug resistance in estrogen receptor (ER)-positive breast cancer (BC). Whether estrogen contributes to ER-negative BC is unclear. Here, we aimed to investigate whether estrogen could stimulate the secretion of stromal-derived f...

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Detalles Bibliográficos
Autores principales: Ouyang, Liquan, Chang, Weilong, Fang, Bin, Qin, Jieting, Qu, Xincai, Cheng, Fanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172230/
https://www.ncbi.nlm.nih.gov/pubmed/27996037
http://dx.doi.org/10.1038/srep39541