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RNA activation of haploinsufficient Foxg1 gene in murine neocortex

More than one hundred distinct gene hemizygosities are specifically linked to epilepsy, mental retardation, autism, schizophrenia and neuro-degeneration. Radical repair of these gene deficits via genome engineering is hardly feasible. The same applies to therapeutic stimulation of the spared allele...

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Detalles Bibliográficos
Autores principales:	Fimiani, Cristina, Goina, Elisa, Su, Qin, Gao, Guangping, Mallamaci, Antonello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172352/ https://www.ncbi.nlm.nih.gov/pubmed/27995975 http://dx.doi.org/10.1038/srep39311

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