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A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers
Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide and is etiologically linked to several cancers, including cervical and genital cancers. NKG2D, an activating receptor expressed by NK cells, plays an important role in cancer immune-surveillance. We analyzed the impac...
Autores principales: | Espinoza, J. Luis, Nguyen, Viet H., Ichimura, Hiroshi, Pham, Trang T. T., Nguyen, Cuong H., Pham, Thuc V., Elbadry, Mahmoud I., Yoshioka, Katsuji, Tanaka, Junji, Trung, Ly Q., Takami, Akiyoshi, Nakao, Shinji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172372/ https://www.ncbi.nlm.nih.gov/pubmed/27995954 http://dx.doi.org/10.1038/srep39231 |
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