Zebrafish Model for Functional Screening of Flow-Responsive Genes

OBJECTIVE—: Atherosclerosis is initiated at branches and bends of arteries exposed to disturbed blood flow that generates low shear stress. This mechanical environment promotes lesions by inducing endothelial cell (EC) apoptosis and dysfunction via mechanisms that are incompletely understood. Althou...

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Detalles Bibliográficos
Autores principales: Serbanovic-Canic, Jovana, de Luca, Amalia, Warboys, Christina, Ferreira, Pedro F., Luong, Le A., Hsiao, Sarah, Gauci, Ismael, Mahmoud, Marwa, Feng, Shuang, Souilhol, Celine, Bowden, Neil, Ashton, John-Paul, Walczak, Henning, Firmin, David, Krams, Rob, Mason, Justin C., Haskard, Dorian O., Sherwin, Spencer, Ridger, Victoria, Chico, Timothy J.A., Evans, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172514/
https://www.ncbi.nlm.nih.gov/pubmed/27834691
http://dx.doi.org/10.1161/ATVBAHA.116.308502

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