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Viral Decay Dynamics and Mathematical Modeling of Treatment Response: Evidence of Lower in vivo Fitness of HIV-1 Subtype C

BACKGROUND: Despite the high prevalence of HIV-1 subtype C (HIV-1C) worldwide, information on HIV-1C viral dynamics and response to antiretroviral therapy (ART) is limited. We sought to measure viral load decay dynamics during treatment and estimate the within-host basic reproductive ratio, R(0), an...

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Detalles Bibliográficos
Autores principales:	Shet, Anita, Nagaraja, Pradeep, Dixit, Narendra M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Materias:	Basic and Translational Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172519/ https://www.ncbi.nlm.nih.gov/pubmed/27273158 http://dx.doi.org/10.1097/QAI.0000000000001101

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