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IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

BACKGROUND: Pediatric acute lymphoblastic leukemia (ALL) is the most common childhood cancer and the leading cause of cancer-related mortality in children. T cell ALL (T-ALL) represents about 15% of pediatric ALL cases and is considered a high-risk disease. T-ALL is often associated with resistance...

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Detalles Bibliográficos
Autores principales:	Li, Yunlei, Buijs-Gladdines, Jessica G. C. A. M., Canté-Barrett, Kirsten, Stubbs, Andrew P., Vroegindeweij, Eric M., Smits, Willem K., van Marion, Ronald, Dinjens, Winand N. M., Horstmann, Martin, Kuiper, Roland P., Buijsman, Rogier C., Zaman, Guido J. R., van der Spek, Peter J., Pieters, Rob, Meijerink, Jules P. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172551/ https://www.ncbi.nlm.nih.gov/pubmed/27997540 http://dx.doi.org/10.1371/journal.pmed.1002200

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