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The Heat Shock Transcription Factor HSF1 Induces Ovarian Cancer Epithelial-Mesenchymal Transition in a 3D Spheroid Growth Model

Ovarian cancer is the most lethal gynecological cancer, with over 200,000 women diagnosed each year and over half of those cases leading to death. The proteotoxic stress-responsive transcription factor HSF1 is frequently overexpressed in a variety of cancers and is vital to cellular proliferation an...

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Detalles Bibliográficos
Autores principales:	Powell, Chase D., Paullin, Trillitye R., Aoisa, Candice, Menzie, Christopher J., Ubaldini, Ashley, Westerheide, Sandy D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172610/ https://www.ncbi.nlm.nih.gov/pubmed/27997575 http://dx.doi.org/10.1371/journal.pone.0168389

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