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Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage. To define the role of TGFβ signaling in ovarian tumorigenesis, we created a mouse model expressing a constitutively active TGFβ rece...

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Detalles Bibliográficos
Autores principales:	Gao, Yang, Vincent, David F., Davis, Anna Jane, Sansom, Owen J., Bartholin, Laurent, Li, Qinglei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173031/ https://www.ncbi.nlm.nih.gov/pubmed/27344183 http://dx.doi.org/10.18632/oncotarget.10149

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