Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

Reactive oxygen species (ROS) are implicated in tumor transformation. The antioxidant system (AOS) protects cells from ROS damage. However, it is also hijacked by cancers cells to proliferate within the tumor. Thus, identifying proteins altered by redox imbalance in cancer cells is an attractive pro...

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Detalles Bibliográficos
Autores principales: Bracalente, Candelaria, Ibañez, Irene L., Berenstein, Ariel, Notcovich, Cintia, Cerda, María B., Klamt, Fabio, Chernomoretz, Ariel, Durán, Hebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173049/
https://www.ncbi.nlm.nih.gov/pubmed/27206673
http://dx.doi.org/10.18632/oncotarget.9273

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