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Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside

There are still unmet medical needs in the treatment of glioblastoma, the most common and the most aggressive glioma of all brain tumors. Here, we found that O-acetyl GD2 is expressed in surgically resected human glioblastoma tissue. In addition, we demonstrated that 8B6 monoclonal antibody specific...

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Detalles Bibliográficos
Autores principales: Fleurence, Julien, Cochonneau, Denis, Fougeray, Sophie, Oliver, Lisa, Geraldo, Fanny, Terme, Mickaël, Dorvillius, Mylène, Loussouarn, Delphine, Vallette, François, Paris, François, Birklé, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173050/
https://www.ncbi.nlm.nih.gov/pubmed/27172791
http://dx.doi.org/10.18632/oncotarget.9226