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Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer

Aberrant STAT3 activation occurs in most human gastric cancers (GCs) and contributes to the malignant progression of GC, but mechanism(s) underlying aberrant STAT3 remain largely unknown. Here we demonstrated that the gene associated with retinoid interferon-induced mortality 19 (GRIM-19) was severe...

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Detalles Bibliográficos
Autores principales: Huang, Yi, Yang, Meihua, Hu, Huajian, Zhao, Xiaodong, Bao, Liming, Huang, Daochao, Song, Lihua, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173068/
https://www.ncbi.nlm.nih.gov/pubmed/27167343
http://dx.doi.org/10.18632/oncotarget.9167