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MiR-146b-5p overexpression attenuates stemness and radioresistance of glioma stem cells by targeting HuR/lincRNA-p21/β-catenin pathway

A stem-like subpopulation existed in GBM cells, called glioma stem cells (GSCs), might contribute to cancer invasion, angiogenesis, immune evasion, and therapeutic resistance, providing a rationale to eliminate GSCs population and their supporting niche for successful GBM treatment. LincRNA-p21, a n...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Yu, Hongquan, Shen, Yueming, Liu, Yingying, Yang, Zhanshan, Sun, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173075/
https://www.ncbi.nlm.nih.gov/pubmed/27166258
http://dx.doi.org/10.18632/oncotarget.9214