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EZH2 promotes colorectal cancer stem-like cell expansion by activating p21(cip1)-Wnt/β-catenin signaling

Because colorectal cancer (CRC) stem-like cells (CCS-like cells) contribute to poor patient prognosis, these cells are a potential target for CRC therapy. However, the mechanism underlying the maintenance of CCS-like cell properties remains unclear. Here, we found that patients with advanced stage C...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Fang, Luo, Xi, Xiang, Li-Sha, Li, Hong-Tao, Zha, Lin, Li, Ni, He, Jian-Ming, Xie, Gan-Feng, Xie, Xiong, Liang, Hou-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173077/
https://www.ncbi.nlm.nih.gov/pubmed/27172794
http://dx.doi.org/10.18632/oncotarget.9236