Cargando…
Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia
T cell acute lymphoblastic leukemia (T-ALL) develops through accumulation of multiple genomic alterations within T-cell progenitors resulting in clonal heterogeneity among leukemic cells. Human T-ALL xeno-transplantation in immunodeficient mice is a gold standard approach to study leukemia biology a...
Autores principales: | Poglio, Sandrine, Lewandowski, Daniel, Calvo, Julien, Caye, Aurélie, Gros, Audrey, Laharanne, Elodie, Leblanc, Thierry, Landman-Parker, Judith, Baruchel, André, Soulier, Jean, Ballerini, Paola, Clappier, Emmanuelle, Pflumio, Françoise |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173081/ https://www.ncbi.nlm.nih.gov/pubmed/27191650 http://dx.doi.org/10.18632/oncotarget.9313 |
Ejemplares similares
-
Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
por: Clappier, Emmanuelle, et al.
Publicado: (2011) -
Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity
por: Poglio, Sandrine, et al.
Publicado: (2020) -
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia
por: Kusy, Sophie, et al.
Publicado: (2010) -
Ikaros deficiency is associated with aggressive BCR-ABL1 B-cell precursor acute lymphoblastic leukemia independent of the lineage and developmental origin
por: Simand, Célestine, et al.
Publicado: (2021) -
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models
por: Thiollier, Clarisse, et al.
Publicado: (2012)