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Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas

Cytoplasmic polyadenylation element binding proteins (CPEBs) are auxiliary translational factors that associate with consensus sequences present in 3′UTRs of mRNAs, thereby activating or repressing their translation. Knowing that CPEBs are players in cell cycle regulation and cellular senescence pro...

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Detalles Bibliográficos
Autores principales: Skubal, Magdalena, Gielen, Gerrit H., Waha, Anke, Gessi, Marco, Kaczmarczyk, Lech, Seifert, Gerald, Freihoff, Dorothee, Freihoff, Johannes, Pietsch, Torsten, Simon, Matthias, Theis, Martin, Steinhäuser, Christian, Waha, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173104/
https://www.ncbi.nlm.nih.gov/pubmed/27256982
http://dx.doi.org/10.18632/oncotarget.9735