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Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism
Colon cancer is a common cause of cancer death in the Western world. Accumulating evidence supports a protective role of estrogen via estrogen receptor beta (ERβ) but the mechanism of action is not known. Here, we elucidate a molecular mechanism whereby ERβ represses the oncogenic prospero homebox 1...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173124/ https://www.ncbi.nlm.nih.gov/pubmed/27283988 http://dx.doi.org/10.18632/oncotarget.9895 |