Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis

Malignant gliomas are difficult to treat in clinical practice. This study was aimed to investigate the preclinical efficacy of CRLX101, an investigational nanoparticle-drug conjugate developed by conjugating camptothecin (CPT) with cyclodextrin-polyethylene glycol, against gliomas. CPT fluorescence...

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Detalles Bibliográficos
Autores principales: Lin, Chien-Ju, Lin, Yi-Ling, Luh, Frank, Yen, Yun, Chen, Ruei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173144/
https://www.ncbi.nlm.nih.gov/pubmed/27285755
http://dx.doi.org/10.18632/oncotarget.9878

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