WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck

Wolf-Hisrchhorn Syndrome Candidate 1-Like 1 (WHSC1L1) is a protein lysine methyltransferase that is recurrently amplified (8p11.23) in patients with squamous cell carcinoma of the head and neck (SCCHN). In this study, we investigated the oncogenic role of WHSC1L1 in SCCHN. Using immunohistochemistry...

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Detalles Bibliográficos
Autores principales: Saloura, Vassiliki, Vougiouklakis, Theodore, Zewde, Makda, Kiyotani, Kazuma, Park, Jae-Hyun, Gao, Guimin, Karrison, Theodore, Lingen, Mark, Nakamura, Yusuke, Hamamoto, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173153/
https://www.ncbi.nlm.nih.gov/pubmed/27285764
http://dx.doi.org/10.18632/oncotarget.9897

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