Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas

Pancreatic cancer is still a disease of high mortality despite availability of diagnostic techniques. Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in pancreatic neoplasms. MUC1 and MUC4 are high molecular weight transmembrane mucins. These are overexpressed in many carcinomas...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Seiya, Higashi, Michiyo, Kitamoto, Sho, Oeldorf, Monika, Knippschild, Uwe, Kornmann, Marko, Maemura, Kosei, Kurahara, Hiroshi, Wiest, Edwin, Hamada, Tomofumi, Kitazono, Ikumi, Goto, Yuko, Tasaki, Takashi, Hiraki, Tsubasa, Hatanaka, Kazuhito, Mataki, Yuko, Taguchi, Hiroki, Hashimoto, Shinichi, Batra, Surinder K., Tanimoto, Akihide, Yonezawa, Suguru, Hollingsworth, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173155/
https://www.ncbi.nlm.nih.gov/pubmed/27283771
http://dx.doi.org/10.18632/oncotarget.9924

Ejemplares similares

Ejemplares similares