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The biology of DHX9 and its potential as a therapeutic target

DHX9 is member of the DExD/H-box family of helicases with a “DEIH” sequence at its eponymous DExH-box motif. Initially purified from human and bovine cells and identified as a homologue of the Drosophila Maleless (MLE) protein, it is an NTP-dependent helicase consisting of a conserved helicase core...

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Detalles Bibliográficos
Autores principales: Lee, Teresa, Pelletier, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173168/
https://www.ncbi.nlm.nih.gov/pubmed/27034008
http://dx.doi.org/10.18632/oncotarget.8446

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