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Immunogenicity and Protective Efficacy of the DAR-901 Booster Vaccine in a Murine Model of Tuberculosis

BACKGROUND: The development of a novel tuberculosis vaccine is a leading global health priority. SRL172, an inactivated, whole-cell mycobacterial vaccine, was safe, immunogenic and reduced the incidence of culture-confirmed tuberculosis in a phase III trial in HIV-infected and BCG immunized adults i...

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Detalles Bibliográficos
Autores principales:	Lahey, Timothy, Laddy, Dominick, Hill, Krystal, Schaeffer, Jacqueline, Hogg, Alison, Keeble, James, Dagg, Belinda, Ho, Mei Mei, Arbeit, Robert D., von Reyn, C. Fordham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173179/ https://www.ncbi.nlm.nih.gov/pubmed/27997597 http://dx.doi.org/10.1371/journal.pone.0168521

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