Essential Genes Embody Increased Mutational Robustness to Compensate for the Lack of Backup Genetic Redundancy

Genetic robustness is a hallmark of cells, occurring through many mechanisms and at many levels. Essential genes lack the common robustness mechanism of genetic redundancy (i.e., existing alongside other genes with the same function), and thus appear at first glance to leave cells highly vulnerable...

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Detalles Bibliográficos
Autores principales: Cohen, Osher, Oberhardt, Matthew, Yizhak, Keren, Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173180/
https://www.ncbi.nlm.nih.gov/pubmed/27997585
http://dx.doi.org/10.1371/journal.pone.0168444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173180/
https://www.ncbi.nlm.nih.gov/pubmed/27997585
http://dx.doi.org/10.1371/journal.pone.0168444

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