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Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines
CD8(+) cytotoxic T lymphocytes (CTLs) are critical for clearing many viral infections, and protective CTL memory can be induced by vaccination with attenuated viruses and vectors. Non-replicating vaccines are typically potentiated by the addition of adjuvants that enhance humoral responses, however...
Autores principales: | Gasper, David J., Neldner, Brandon, Plisch, Erin H., Rustom, Hani, Carrow, Emily, Imai, Hirotaka, Kawaoka, Yoshihiro, Suresh, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173246/ https://www.ncbi.nlm.nih.gov/pubmed/27997610 http://dx.doi.org/10.1371/journal.ppat.1006064 |
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