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COX7A2L/SCAFI and Pre-Complex III Modify Respiratory Chain Supercomplex Formation in Different Mouse Strains with a Bcs1l Mutation

The COX7A2L (Supercomplex Assembly Factor I, SCAFI) protein has been proposed to be a mitochondrial supercomplex assembly factor required for respirasome (supercomplex containing complexes I, III, and IV) formation. In the C57BL/6 mouse strain a homozygous in-frame 6-base-pair deletion in the COX7a2...

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Detalles Bibliográficos
Autores principales: Davoudi, Mina, Kotarsky, Heike, Hansson, Eva, Kallijärvi, Jukka, Fellman, Vineta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173253/
https://www.ncbi.nlm.nih.gov/pubmed/27997587
http://dx.doi.org/10.1371/journal.pone.0168774