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cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation

Elucidating the mechanisms involved in sensitizing radioresistant tumors to ionizing radiation (IR) treatments while minimizing injury to surrounding normal tissue is an important clinical goal. Due to their sequence-derived specificity and properties as gene regulators in IR-affected pathways, micr...

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Detalles Bibliográficos
Autores principales: Metheetrairut, Chanatip, Adams, Brian D., Nallur, Sunitha, Weidhaas, Joanne B., Slack, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173455/
https://www.ncbi.nlm.nih.gov/pubmed/27321180
http://dx.doi.org/10.1038/onc.2016.222