Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency

A 57-year-old man with antithrombin III deficiency with deep vein thrombosis and pulmonary thromboembolism after surgery for colon cancer was managed with warfarin and inferior vena cava filtration. After starting chemotherapy for liver metastasis, the control of his prothrombin time-international n...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawano, Hiroaki, Maemura, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173495/
https://www.ncbi.nlm.nih.gov/pubmed/27853070
_version_ 1782484317455253504
author Kawano, Hiroaki
Maemura, Koji
author_facet Kawano, Hiroaki
Maemura, Koji
author_sort Kawano, Hiroaki
collection PubMed
description A 57-year-old man with antithrombin III deficiency with deep vein thrombosis and pulmonary thromboembolism after surgery for colon cancer was managed with warfarin and inferior vena cava filtration. After starting chemotherapy for liver metastasis, the control of his prothrombin time-international normalized ratio in response to warfarin began to fluctuate. Warfarin was changed to edoxaban (an oral direct Factor Xa inhibitor), and he had no recurrence of venous thromboembolism or bleeding for approximately 1 year. We conclude that edoxaban could be a useful treatment option for complicated patients with deep vein thrombosis.
format Online
Article
Text
id pubmed-5173495
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-51734952016-12-27 Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency Kawano, Hiroaki Maemura, Koji Intern Med Case Report A 57-year-old man with antithrombin III deficiency with deep vein thrombosis and pulmonary thromboembolism after surgery for colon cancer was managed with warfarin and inferior vena cava filtration. After starting chemotherapy for liver metastasis, the control of his prothrombin time-international normalized ratio in response to warfarin began to fluctuate. Warfarin was changed to edoxaban (an oral direct Factor Xa inhibitor), and he had no recurrence of venous thromboembolism or bleeding for approximately 1 year. We conclude that edoxaban could be a useful treatment option for complicated patients with deep vein thrombosis. The Japanese Society of Internal Medicine 2016-11-15 /pmc/articles/PMC5173495/ /pubmed/27853070 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kawano, Hiroaki
Maemura, Koji
Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency
title Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency
title_full Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency
title_fullStr Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency
title_full_unstemmed Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency
title_short Edoxaban Was Effective for the Treatment of Deep Vein Thrombosis and Pulmonary Thromboembolism in a Cancer Patient with Antithrombin III Deficiency
title_sort edoxaban was effective for the treatment of deep vein thrombosis and pulmonary thromboembolism in a cancer patient with antithrombin iii deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173495/
https://www.ncbi.nlm.nih.gov/pubmed/27853070
work_keys_str_mv AT kawanohiroaki edoxabanwaseffectiveforthetreatmentofdeepveinthrombosisandpulmonarythromboembolisminacancerpatientwithantithrombiniiideficiency
AT maemurakoji edoxabanwaseffectiveforthetreatmentofdeepveinthrombosisandpulmonarythromboembolisminacancerpatientwithantithrombiniiideficiency

Ejemplares similares