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Definitive Chemoradiotherapy for Advanced Pulmonary Sarcomatoid Carcinoma

Pulmonary sarcomatoid carcinoma is a rare subtype of non-small cell lung cancer with a poor prognosis. We herein report on a case of pulmonary sarcomatoid carcinoma that was treated successfully by concurrent chemoradiotherapy. A 65-year-old man was diagnosed to have pulmonary pleomorphic carcinoma...

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Detalles Bibliográficos
Autores principales: Takeda, Kazuya, Matsushita, Haruo, Kubozono, Masaki, Tanabe, Takaya, Ishikawa, Yojiro, Yamamoto, Takaya, Kozumi, Maiko, Takahashi, Noriyoshi, Katagiri, Yu, Tasaka, Shun, Fukui, Katsuya, Takeda, Ken, Fujishima, Fumiyoshi, Ichinose, Masakazu, Jingu, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173502/
https://www.ncbi.nlm.nih.gov/pubmed/27853077
Descripción
Sumario:Pulmonary sarcomatoid carcinoma is a rare subtype of non-small cell lung cancer with a poor prognosis. We herein report on a case of pulmonary sarcomatoid carcinoma that was treated successfully by concurrent chemoradiotherapy. A 65-year-old man was diagnosed to have pulmonary pleomorphic carcinoma (clinical T4N2M0 stage IIIB). He received concurrent chemoradiotherapy (60 Gy of radiotherapy in 30 fractionations and two courses of chemotherapy with carboplatin and paclitaxel). After chemoradiotherapy, a significant reduction of the tumor size was observed. Two courses of adjuvant chemotherapy were performed. He is currently alive at 15 months after the first treatment without any recurrence or metastasis.