Recurrent Bilateral Focal Myositis

This report describes a rare case of recurrent bilateral focal myositis and its successful treatment via methotrexate. A 38-year-old man presented myalgia of the right gastrocnemius in May 2005. Magnetic resonance imaging showed very high signal intensity in the right gastrocnemius on short-tau inve...

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Autores principales: Nagafuchi, Hiroko, Nakano, Hiromasa, Ooka, Seido, Takakuwa, Yukiko, Yamada, Hidehiro, Tadokoro, Mamoru, Shimojo, Sadatomo, Ozaki, Shoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173511/
https://www.ncbi.nlm.nih.gov/pubmed/27853086
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author Nagafuchi, Hiroko
Nakano, Hiromasa
Ooka, Seido
Takakuwa, Yukiko
Yamada, Hidehiro
Tadokoro, Mamoru
Shimojo, Sadatomo
Ozaki, Shoichi
author_facet Nagafuchi, Hiroko
Nakano, Hiromasa
Ooka, Seido
Takakuwa, Yukiko
Yamada, Hidehiro
Tadokoro, Mamoru
Shimojo, Sadatomo
Ozaki, Shoichi
author_sort Nagafuchi, Hiroko
collection PubMed
description This report describes a rare case of recurrent bilateral focal myositis and its successful treatment via methotrexate. A 38-year-old man presented myalgia of the right gastrocnemius in May 2005. Magnetic resonance imaging showed very high signal intensity in the right gastrocnemius on short-tau inversion recovery images. A muscle biopsy revealed inflammatory CD4+ cell-dominant myogenic change. Focal myositis was diagnosed. The first steroid treatment was effective. Tapering of prednisolone, however, repeatedly induced myositis relapse, which progressed to multiple muscle lesions of both lower limbs. Initiation of methotrexate finally allowed successful tapering of prednisolone, with no relapse in the past 4 years.
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spelling pubmed-51735112016-12-27 Recurrent Bilateral Focal Myositis Nagafuchi, Hiroko Nakano, Hiromasa Ooka, Seido Takakuwa, Yukiko Yamada, Hidehiro Tadokoro, Mamoru Shimojo, Sadatomo Ozaki, Shoichi Intern Med Case Report This report describes a rare case of recurrent bilateral focal myositis and its successful treatment via methotrexate. A 38-year-old man presented myalgia of the right gastrocnemius in May 2005. Magnetic resonance imaging showed very high signal intensity in the right gastrocnemius on short-tau inversion recovery images. A muscle biopsy revealed inflammatory CD4+ cell-dominant myogenic change. Focal myositis was diagnosed. The first steroid treatment was effective. Tapering of prednisolone, however, repeatedly induced myositis relapse, which progressed to multiple muscle lesions of both lower limbs. Initiation of methotrexate finally allowed successful tapering of prednisolone, with no relapse in the past 4 years. The Japanese Society of Internal Medicine 2016-11-15 /pmc/articles/PMC5173511/ /pubmed/27853086 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nagafuchi, Hiroko
Nakano, Hiromasa
Ooka, Seido
Takakuwa, Yukiko
Yamada, Hidehiro
Tadokoro, Mamoru
Shimojo, Sadatomo
Ozaki, Shoichi
Recurrent Bilateral Focal Myositis
title Recurrent Bilateral Focal Myositis
title_full Recurrent Bilateral Focal Myositis
title_fullStr Recurrent Bilateral Focal Myositis
title_full_unstemmed Recurrent Bilateral Focal Myositis
title_short Recurrent Bilateral Focal Myositis
title_sort recurrent bilateral focal myositis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173511/
https://www.ncbi.nlm.nih.gov/pubmed/27853086
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AT tadokoromamoru recurrentbilateralfocalmyositis
AT shimojosadatomo recurrentbilateralfocalmyositis
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