Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?

Avian leukosis virus (ALV) is an avian oncogenic retrovirus causing enormous economic losses in the global poultry industry. Although ALV-related research has lasted for more than a century, there are no vaccines to protect chickens from ALV infection. The interaction between chickens and ALV remain...

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Detalles Bibliográficos
Autores principales: Feng, Min, Zhang, Xiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174080/
https://www.ncbi.nlm.nih.gov/pubmed/28066434
http://dx.doi.org/10.3389/fimmu.2016.00624
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author Feng, Min
Zhang, Xiquan
author_facet Feng, Min
Zhang, Xiquan
author_sort Feng, Min
collection PubMed
description Avian leukosis virus (ALV) is an avian oncogenic retrovirus causing enormous economic losses in the global poultry industry. Although ALV-related research has lasted for more than a century, there are no vaccines to protect chickens from ALV infection. The interaction between chickens and ALV remains not fully understood especially with regard to the host immunity. The current review provides an overview of our current knowledge of innate and adaptive immunity induced by ALV infection. More importantly, we have pointed out the unknown area involved in ALV-related studies, which is worthy of our serious exploring in future.
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spelling pubmed-51740802017-01-06 Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do? Feng, Min Zhang, Xiquan Front Immunol Immunology Avian leukosis virus (ALV) is an avian oncogenic retrovirus causing enormous economic losses in the global poultry industry. Although ALV-related research has lasted for more than a century, there are no vaccines to protect chickens from ALV infection. The interaction between chickens and ALV remains not fully understood especially with regard to the host immunity. The current review provides an overview of our current knowledge of innate and adaptive immunity induced by ALV infection. More importantly, we have pointed out the unknown area involved in ALV-related studies, which is worthy of our serious exploring in future. Frontiers Media S.A. 2016-12-21 /pmc/articles/PMC5174080/ /pubmed/28066434 http://dx.doi.org/10.3389/fimmu.2016.00624 Text en Copyright © 2016 Feng and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Feng, Min
Zhang, Xiquan
Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?
title Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?
title_full Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?
title_fullStr Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?
title_full_unstemmed Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?
title_short Immunity to Avian Leukosis Virus: Where Are We Now and What Should We Do?
title_sort immunity to avian leukosis virus: where are we now and what should we do?
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174080/
https://www.ncbi.nlm.nih.gov/pubmed/28066434
http://dx.doi.org/10.3389/fimmu.2016.00624
work_keys_str_mv AT fengmin immunitytoavianleukosisviruswherearewenowandwhatshouldwedo
AT zhangxiquan immunitytoavianleukosisviruswherearewenowandwhatshouldwedo

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