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Membrane Proteomics Analysis of the Candida glabrata Response to 5-Flucytosine: Unveiling the Role and Regulation of the Drug Efflux Transporters CgFlr1 and CgFlr2

Resistance to 5-flucytosine (5-FC), used as an antifungal drug in combination therapy, compromises its therapeutic action. In this work, the response of the human pathogen Candida glabrata to 5-FC was evaluated at the membrane proteome level, using an iTRAQ-based approach. A total of 32 proteins wer...

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Detalles Bibliográficos
Autores principales:	Pais, Pedro, Pires, Carla, Costa, Catarina, Okamoto, Michiyo, Chibana, Hiroji, Teixeira, Miguel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174090/ https://www.ncbi.nlm.nih.gov/pubmed/28066366 http://dx.doi.org/10.3389/fmicb.2016.02045

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