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Pleomorphic adenoma of the larynx
Pleomorphic adenoma (PA) is the most common benign neoplasm of the salivary glands. It usually occurs in major salivary glands, such as the parotid and submandibular glands. Occasionally, however, it occurs in the larynx. These lesions generally present as a slow-growing, painless mass. Malignant tr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175081/ https://www.ncbi.nlm.nih.gov/pubmed/28058389 http://dx.doi.org/10.14744/nci.2015.47965 |
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author | Altunpulluk, Meryem Doğan Karabulut, Murat Hakan Kır, Gözde Şahin, Şamil |
author_facet | Altunpulluk, Meryem Doğan Karabulut, Murat Hakan Kır, Gözde Şahin, Şamil |
author_sort | Altunpulluk, Meryem Doğan |
collection | PubMed |
description | Pleomorphic adenoma (PA) is the most common benign neoplasm of the salivary glands. It usually occurs in major salivary glands, such as the parotid and submandibular glands. Occasionally, however, it occurs in the larynx. These lesions generally present as a slow-growing, painless mass. Malignant transformation is very rare, but it increases with time. The present report is the case of a 59-year-old male who presented with a complaint of hoarseness. Right vertical partial hemilaryngectomy revealed an intact, mucosa-covered, fleshy 2×1.5×1 cm mass in the supraglottic area of the larynx. Lesion had histological characteristics of a PA, and this was confirmed by immunohistochemical expression of cytokeratin, S100 protein, Glial fibrillary acidic protein (GFAP) and vimentin. Their histopathological identification is, however, not always straightforward; immunohistochemistry can contribute significantly to formulation of a definitive diagnosis and to the realization of appropriate follow-up. |
format | Online Article Text |
id | pubmed-5175081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-51750812017-01-05 Pleomorphic adenoma of the larynx Altunpulluk, Meryem Doğan Karabulut, Murat Hakan Kır, Gözde Şahin, Şamil North Clin Istanb Case Report Pleomorphic adenoma (PA) is the most common benign neoplasm of the salivary glands. It usually occurs in major salivary glands, such as the parotid and submandibular glands. Occasionally, however, it occurs in the larynx. These lesions generally present as a slow-growing, painless mass. Malignant transformation is very rare, but it increases with time. The present report is the case of a 59-year-old male who presented with a complaint of hoarseness. Right vertical partial hemilaryngectomy revealed an intact, mucosa-covered, fleshy 2×1.5×1 cm mass in the supraglottic area of the larynx. Lesion had histological characteristics of a PA, and this was confirmed by immunohistochemical expression of cytokeratin, S100 protein, Glial fibrillary acidic protein (GFAP) and vimentin. Their histopathological identification is, however, not always straightforward; immunohistochemistry can contribute significantly to formulation of a definitive diagnosis and to the realization of appropriate follow-up. Kare Publishing 2016-04-04 /pmc/articles/PMC5175081/ /pubmed/28058389 http://dx.doi.org/10.14744/nci.2015.47965 Text en Copyright: © Istanbul Northern Anatolian Association of Public Hospitals http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License |
spellingShingle | Case Report Altunpulluk, Meryem Doğan Karabulut, Murat Hakan Kır, Gözde Şahin, Şamil Pleomorphic adenoma of the larynx |
title | Pleomorphic adenoma of the larynx |
title_full | Pleomorphic adenoma of the larynx |
title_fullStr | Pleomorphic adenoma of the larynx |
title_full_unstemmed | Pleomorphic adenoma of the larynx |
title_short | Pleomorphic adenoma of the larynx |
title_sort | pleomorphic adenoma of the larynx |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175081/ https://www.ncbi.nlm.nih.gov/pubmed/28058389 http://dx.doi.org/10.14744/nci.2015.47965 |
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