Suppression of NLRP3 Inflammasome Activation Ameliorates Chronic Kidney Disease-Induced Cardiac Fibrosis and Diastolic Dysfunction

Cardiac fibrosis is a common finding in patients with chronic kidney disease. Here, we investigate the cardio-renal effects of theracurmin, a novel formulation of the polyphenolic compound curcumin, in a rat model of chronic kidney disease. Briefly, Sprague-Dawley rats were randomized to undergo sha...

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Detalles Bibliográficos
Autores principales: Bugyei-Twum, Antoinette, Abadeh, Armin, Thai, Kerri, Zhang, Yanling, Mitchell, Melissa, Kabir, Golam, Connelly, Kim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175152/
https://www.ncbi.nlm.nih.gov/pubmed/28000751
http://dx.doi.org/10.1038/srep39551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175152/
https://www.ncbi.nlm.nih.gov/pubmed/28000751
http://dx.doi.org/10.1038/srep39551

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