Protein Inhibitor of Activated STAT Y (PIASy) Regulates Insulin Secretion by Interacting with LIM Homeodomain Transcription Factor Isl1

It is known that the LIM homeodomain transcription factor Isl1 is highly expressed in all pancreatic endocrine cells and functions in regulating pancreatic development and insulin secretion. The Isl1 mutation has been found to be associated with type 2 diabetes, but the mechanism responsible for Isl...

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Detalles Bibliográficos
Autores principales: Yan, Chengzhi, Yu, Chulin, Zhang, Di, Cui, Yan, Zhou, Jinlian, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175275/
https://www.ncbi.nlm.nih.gov/pubmed/28000708
http://dx.doi.org/10.1038/srep39308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175275/
https://www.ncbi.nlm.nih.gov/pubmed/28000708
http://dx.doi.org/10.1038/srep39308

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