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Protein Inhibitor of Activated STAT Y (PIASy) Regulates Insulin Secretion by Interacting with LIM Homeodomain Transcription Factor Isl1
It is known that the LIM homeodomain transcription factor Isl1 is highly expressed in all pancreatic endocrine cells and functions in regulating pancreatic development and insulin secretion. The Isl1 mutation has been found to be associated with type 2 diabetes, but the mechanism responsible for Isl...
Autores principales: | Yan, Chengzhi, Yu, Chulin, Zhang, Di, Cui, Yan, Zhou, Jinlian, Cui, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175275/ https://www.ncbi.nlm.nih.gov/pubmed/28000708 http://dx.doi.org/10.1038/srep39308 |
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