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Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging

The penetration of anticancer drugs in solid tumors is important to ensure the therapeutic effect, so methods are needed to understand drug distribution in different parts of the tumor. Mass spectrometry imaging (MSI) has great potential in this field to visualize drug distribution in organs and tum...

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Detalles Bibliográficos
Autores principales: Giordano, Silvia, Zucchetti, Massimo, Decio, Alessandra, Cesca, Marta, Fuso Nerini, Ilaria, Maiezza, Marika, Ferrari, Mariella, Licandro, Simonetta Andrea, Frapolli, Roberta, Giavazzi, Raffaella, Maurizio, D’Incalci, Davoli, Enrico, Morosi, Lavinia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175283/
https://www.ncbi.nlm.nih.gov/pubmed/28000726
http://dx.doi.org/10.1038/srep39284