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Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo

BACKGROUND: Despite the durable viral suppression afforded by antiretroviral therapy, HIV-1 eradication will require strategies to target latently infected cells that persist in infected individuals. Protein kinase C (PKC) activation is a promising strategy to reactivate latent proviruses and allow...

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Detalles Bibliográficos
Autores principales:	Spivak, Adam M., Larragoite, Erin T., Coletti, McKenna L., Macedo, Amanda B., Martins, Laura J., Bosque, Alberto, Planelles, Vicente
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175306/ https://www.ncbi.nlm.nih.gov/pubmed/27998278 http://dx.doi.org/10.1186/s12977-016-0319-0

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