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Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

BACKGROUND: Although next generation sequencing (NGS) offers the potential for studying virus populations in unprecedented depth, PCR error, amplification bias and recombination during library construction have limited its use to population sequencing and measurements of unlinked allele frequencies....

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Detalles Bibliográficos
Autores principales:	Boltz, Valerie F., Rausch, Jason, Shao, Wei, Hattori, Junko, Luke, Brian, Maldarelli, Frank, Mellors, John W., Kearney, Mary F., Coffin, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175307/ https://www.ncbi.nlm.nih.gov/pubmed/27998286 http://dx.doi.org/10.1186/s12977-016-0321-6

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