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The functional requirement of two structural domains within telomerase RNA emerged early in eukaryotes

Telomerase emerged during evolution as a prominent solution to the eukaryotic linear chromosome end-replication problem. Telomerase minimally comprises the catalytic telomerase reverse transcriptase (TERT) and telomerase RNA (TR) that provides the template for telomeric DNA synthesis. While the TERT...

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Detalles Bibliográficos
Autores principales:	Podlevsky, Joshua D., Li, Yang, Chen, Julian J.-L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175330/ https://www.ncbi.nlm.nih.gov/pubmed/27378779 http://dx.doi.org/10.1093/nar/gkw605

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