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An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase

Helicases couple ATP hydrolysis to nucleic acid binding and unwinding via molecular mechanisms that remain poorly defined for most enzyme subfamilies within the superfamily 2 (SF2) helicase group. A crystal structure of the PriA SF2 DNA helicase, which governs restart of prematurely terminated repli...

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Detalles Bibliográficos
Autores principales: Windgassen, Tricia A., Keck, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175346/
https://www.ncbi.nlm.nih.gov/pubmed/27484483
http://dx.doi.org/10.1093/nar/gkw690

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