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Molecular basis of cobalamin-dependent RNA modification

Queuosine (Q) was discovered in the wobble position of a transfer RNA (tRNA) 47 years ago, yet the final biosynthetic enzyme responsible for Q-maturation, epoxyqueuosine (oQ) reductase (QueG), was only recently identified. QueG is a cobalamin (Cbl)-dependent, [4Fe-4S] cluster-containing protein that...

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Detalles Bibliográficos
Autores principales:	Dowling, Daniel P., Miles, Zachary D., Köhrer, Caroline, Maiocco, Stephanie J., Elliott, Sean J., Bandarian, Vahe, Drennan, Catherine L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175355/ https://www.ncbi.nlm.nih.gov/pubmed/27638883 http://dx.doi.org/10.1093/nar/gkw806

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