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5-methylcytosine-sensitive variants of Thermococcus kodakaraensis DNA polymerase
DNA methylation of cytosine in eukaryotic cells is a common epigenetic modification, which plays an important role in gene expression and thus affects various cellular processes like development and carcinogenesis. The occurrence of 5-methyl-2′-deoxycytosine (5mC) as well as the distribution pattern...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175357/ https://www.ncbi.nlm.nih.gov/pubmed/27651460 http://dx.doi.org/10.1093/nar/gkw812 |