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hLARP7 C-terminal domain contains an xRRM that binds the 3′ hairpin of 7SK RNA

The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and inactivates the positive transcription elongation factor b (P-TEFb), an essential eukaryotic mRNA transcription factor. The human La-related protein group 7 (hLARP7) is a constitutive component of the 7SK snRNP and localizes to the 3′ te...

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Detalles Bibliográficos
Autores principales:	Eichhorn, Catherine D., Chug, Rahul, Feigon, Juli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175362/ https://www.ncbi.nlm.nih.gov/pubmed/27679474 http://dx.doi.org/10.1093/nar/gkw833

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